2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-183574
    Antimalarial agent 62
    		Inhibitor
    Antimalarial agent 62 is an orally active imidazopyridine-6-carboxamide antimalarial agent with a high resistance barrier. Antimalarial agent 62 kills trophozoite-stage Plasmodium ring forms, effectively clears dihydroartemisinin-induced dormant Plasmodium ring forms, and eliminates parasitemia in mice infected with Plasmodium yoelii. In AReBaR resistance omics screening, Antimalarial agent 62 is not affected by different target- and efflux-mediated resistance mutations and can withstand resistance selection. Antimalarial agent 62 has been applied to studies of malaria-related mechanisms.
    Antimalarial agent 62
  • HY-B1036R
    Decoquinate (Standard)
    		Inhibitor
    Decoquinate (Standard) is the analytical standard of Decoquinate. This product is intended for research and analytical applications. Decoquinate is a quinolone derivative that can be used for research of coccidiosis in domestic ruminants. Decoquinate also has potent activity against both Plasmodium hepatic development and red cell replication.
    Decoquinate (Standard)
  • HY-N14198
    Hynapene C
    		Inhibitor
    Hynapene A inhibits Eimeria tenella with a MIC of 34.7 μM.
    Hynapene C
  • HY-B0817R
    Pyridaben (Standard)
    		Inhibitor
    Pyridaben (Standard) is the analytical standard of Pyridaben. This product is intended for research and analytical applications. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function.
    Pyridaben (Standard)
  • HY-W010254R
    4′-Hydroxy-2′-methylacetophenone (Standard)
    		Inhibitor
    4′-Hydroxy-2′-methylacetophenone (Standard) is the analytical standard of 4′-Hydroxy-2′-methylacetophenone (HY-W010254). This product is intended for research and analytical applications. 4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM.
    4′-Hydroxy-2′-methylacetophenone (Standard)
  • HY-B2098R
    Lucanthone (Standard)
    Lucanthone (Standard) is the analytical standard of Lucanthone. This product is intended for research and analytical applications. Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).
    Lucanthone (Standard)
  • HY-B2028
    Propargite
    		Inhibitor
    Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50?of?1?μM. Propargite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargite
  • HY-182685
    MMV693183
    		Inhibitor
    MMV693183 is an orally active inhibitor of Plasmodium falciparum acetyl-CoA synthetase (AcAS), with an IC50 of 300 nM against Plasmodium falciparum. MMV693183 exhibits potent inhibitory activity against clinical isolates of malaria parasites, including Artemisinin (HY-B0094)-resistant strains. MMV693183 is metabolized in vivo into the active antimetabolite CoA-MMV693183, which exerts effects of killing asexual blood-stage parasites and blocking transmission to Anopheles mosquitoes by binding to and inhibiting the function of acetyl-CoA synthetase, thereby reducing the levels of acetyl-CoA and 4'-phosphopantetheine. In humanized mouse models, MMV693183 shows favorable in vivo efficacy, drug-like properties, and no significant cytotoxicity or off-target activity against human cells. MMV693183 is widely used in malaria-related research as a parasiticide and metabolic disruptor.
    MMV693183
  • HY-17597R
    Febantel (Standard)
    		Inhibitor
    Febantel (Standard) is the analytical standard of Febantel. This product is intended for research and analytical applications. Febantel is an anthelmintic used for roundworm and tapeworm infections in poultry and livestock.
    Febantel (Standard)
  • HY-123251
    DB-766
    		Inhibitor
    DB-766 is an anti-parasite and antileishmanial agent, and is active against T. cruzi. DB-766 effectively reduces the parasite load in the blood and cardiac tissue.
    DB-766
  • HY-N14067
    Cytosaminomycin A
    		Inhibitor
    Cytosaminomycin A is an antibiotic with anticoccidial and antibacterial activities.
    Cytosaminomycin A
  • HY-W040126
    Tn antigen
    		Inhibitor
    Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanosomal activity with an IC50 of >0.5 mM. Tn Antigen can be used for the research of Chagas’ disease.
    Tn antigen
  • HY-101000R
    Clazuril (Standard)
    		Inhibitor
    Clazuril (Standard) is the analytical standard of Clazuril. This product is intended for research and analytical applications. Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle.
    Clazuril (Standard)
  • HY-131300
    Colchicoside
    		Inhibitor 99.37%
    Colchicoside is a bioactive tropolone alkaloid with anti-leishmanial and anti-leishmanial?activities.
    Colchicoside
  • HY-B0226A
    (E)-Nitrofurazone
    		Inhibitor 98.83%
    (E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery.
    (E)-Nitrofurazone
  • HY-B1088R
    Clopidol (Standard)
    		Inhibitor
    Clopidol (Standard) is the analytical standard of Clopidol. This product is intended for research and analytical applications. Clopidol (WR-61112) is an anticoccidial agent which is used as feed additive to control coccidiosis in chickens. Clopidol inhibits the sporulation of Eimeria tenella oocysts.
    Clopidol (Standard)
  • HY-100358R
    AQ-13 dihydrochloride (Standard)
    		Inhibitor
    AQ-13 dihydrochloride (Standard) is the analytical standard of AQ-13 dihydrochloride (HY-100358). This product is intended for research and analytical applications. AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum.
    AQ-13 dihydrochloride (Standard)
  • HY-178033
    Antileishmanial agent-35
    		Inhibitor
    Antileishmanial agent-35 (Compound 6) is an antileishmanial agent with an IC50 of 0.29μM for promastigotes of Leishmania amazonensis. Antileishmanial agent-35 significantly decreases the mitochondrial membrane potential and ATP levels, and further increases the production of ROS by a blockage in the electron transport chain, where ubiquinone intervenes. Antileishmanial agent-35 can be used for cutaneous leishmaniases research.
    Antileishmanial agent-35
  • HY-125419
    Amythiamicin B
    Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum.
    Amythiamicin B
  • HY-126118
    Dienochlor
    Dienochlor (Decachlor) is a miticide that inhibits Mexican bean beetle, Epilachna varivestis Mulsant, from laying eggs on pinto beans.
    Dienochlor
Parasite Isoform Comparison

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